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Gum Disease and your Health Gastric ulcers linked to gum disease 0

The article below shows that H. Pilori is found in dental plaque.  H. Pilori is the bacteria that causes Stomach Ulcers.

LANAP reverses gum disease

ssumpcao MB, Martins LC, Melo Barbosa H, Barile KA, Almeida SS, Assumpcao 
PP, Corvelo TC.Helicobacter pylori in dental plaque and stomach of patients 
from Northern Brazil.   World J Gastroenterol 2010 June;16(24):3033-3039 

Helicobacter pylori in dental plaque and stomach of patients from Northern 

Assumpcao MB, Martins LC, Melo Barbosa H, Barile KA, Almeida SS, Assumpcao 
PP, Corvelo TC. 

Immunogenetics Laboratory, Federal University of Para, 66075-110, Belem, 
Para, Brazil. ter@ufpa.br 

AIM: To establish whether virulence factor genes vacA and cagA are present 
in Helicobacter pylori (H. pylori) retrieved from gastric mucosa and dental 
plaque in patients with dyspepsia. METHODS: Cumulative dental plaque 
specimens and gastric biopsies were submitted to histological examination, 
rapid urease test and polymerase chain reaction (PCR) assays to detect the 
presence of cagA and vacA polymorphisms. RESULTS: Detection of H. pylori 
from dental plaque and gastric biopsy samples was greater by PCR compared to 
histological examination and the rapid urease test. DNA from H. pylori was 
detected in 96% of gastric mucosa samples and in 72% of dental plaque 
samples. Sixty-three (89%) of 71 dental plaque samples that were H. 
pylori-positive also exhibited identical vacA and cagA genotypes in gastric 
mucosa. The most common genotype was vacAs1bm1 and cagA positive, either in 
dental plaque or gastric mucosa. These virulent H. pylori isolates were 
involved in the severity of clinical outcome. CONCLUSION: These pathogenic 
strains were found simultaneously in dental plaque and gastric mucosa, which 
suggests that gastric infection is correlated with the presence of H. pylori 
in the mouth. 

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